ISSN 2146-8389
 

Original Research (Original Article) 


<i>Amaranthus viridis</i> Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system

Ganapathy Saravanan, Ponnusamy Ponmurugan.

Cited by (2)

Abstract
The present study was conducted to evaluate the antioxidant role of <i>Amaranthus viridis</i> Linn against isoproterenol (ISO) induced oxidative damage in plasma and erythrocytes of rats. Subcutaneous injection of ISO to rats for 2 consecutive days offered significant increase in the level of lipid peroxidation products, decreased the activities of antioxidant enzymes and vitamin C, vitamin E and reduced glutathione. The administration of <i>Amaranthus viridis</i> Linn (300 mg/kg body weight) increased the activities of antioxidant enzymes and reduced the concentration of lipid peroxidation products. Concentration of vitamin C, vitamin E and reduced glutathione was also high in <i>A.viridis</i> pretreated rats. The effect produced by <i>A.viridis</i> was compared with α- tocopherol. The present findings have demonstrated that the cardioprotective effects of <i>A.viridis</i> in ISO-induced oxidative damage may be due to an augmentation of the endogenous antioxidants and inhibition of lipid peroxidation.

Key words: Antioxidants; Isoproterenol; Lipid peroxides


 
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This Article Cited By the following articles

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How to Cite this Article
Pubmed Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxid Antioxid Med Sci. 2012; 1(1): 69-73. doi:10.5455/oams.060312.or.002


Web Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. http://www.ejmoams.com/?mno=16940 [Access: September 21, 2019]. doi:10.5455/oams.060312.or.002


AMA (American Medical Association) Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxid Antioxid Med Sci. 2012; 1(1): 69-73. doi:10.5455/oams.060312.or.002



Vancouver/ICMJE Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxid Antioxid Med Sci. (2012), [cited September 21, 2019]; 1(1): 69-73. doi:10.5455/oams.060312.or.002



Harvard Style

Ganapathy Saravanan, Ponnusamy Ponmurugan (2012) Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxid Antioxid Med Sci, 1 (1), 69-73. doi:10.5455/oams.060312.or.002



Turabian Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. 2012. Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxidants and Antioxidants in Medical Science, 1 (1), 69-73. doi:10.5455/oams.060312.or.002



Chicago Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. "Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system." Oxidants and Antioxidants in Medical Science 1 (2012), 69-73. doi:10.5455/oams.060312.or.002



MLA (The Modern Language Association) Style

Ganapathy Saravanan, Ponnusamy Ponmurugan. "Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system." Oxidants and Antioxidants in Medical Science 1.1 (2012), 69-73. Print. doi:10.5455/oams.060312.or.002



APA (American Psychological Association) Style

Ganapathy Saravanan, Ponnusamy Ponmurugan (2012) Amaranthus viridis Linn extract ameliorates isoproterenol-induced cardiac toxicity in rats by stabilizing circulatory antioxidant system. Oxidants and Antioxidants in Medical Science, 1 (1), 69-73. doi:10.5455/oams.060312.or.002





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